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Human iPSC Models from Healthy Donors for Predictive Research

 

Current drug discovery tools often fail to meet modern needs. With the FDA Modernization Act 2.0 reducing reliance on animal-based methods, iPSC models are emerging as more predictive, reliable tools for advancing research and addressing unmet medical needs.

Tebubio, through iXCells Biotechnologies, delivers high-quality, physiologically relevant iPSC models from healthy, normal donors, ready to integrate seamlessly into your research.

Are you struggling to source high-quality human biological samples to meet European guidelines? Explore the Tebubio Webinar to learn how to source the best human biological materials for your project.

 

Expand the Frontiers of Discovery with Human iPSC-derived Models

iXCells human iPSC-derived models enable predictive, reproducible systems for a wide range of applications:

  • Drug Screening & Toxicology: Test compounds in physiologically relevant human cells.

  • Target & Biomarker Discovery: Study disease-specific pathways with greater fidelity.

  • Disease Modelling: Use genome-edited or patient-specific lines.

  • Precision Medicine: Explore age, sex, genotype, and ethnicity variability.

  • 3D Systems & Organoids: Integrate into organ-on-chip, microfluidics, or multi-cell co-culture platforms.

Figure 1: Immunostaining of iPSC-derived sensory neurons expressing MAP2 (green), BRN3A (red), Peripherin (red) 7 days post-thaw. All cells were counterstained for DAPI (blue). Scale bars: 200 µm..

Which iPSC-derived Model Fits Your Research Needs?

Choosing the right model is crucial. Our selection guide simplifies your decision by highlighting the key characteristics and applications of each cell type. 

Selection of iPSC models from normal donors for diverse research applications.

iXCells iPSC Products
Name Reference Description Application
Human Astrocytes 40HU-008 Typical astrocytic morphology; GFAP & ALDH1L1 positive; responsive to inflammation. Multi-cellular Central Nervous System (CNS) models.
Human Cortical Neurons 40HU-009 Pure, functional cortical neurons; TBR1, TUJ1, synaptic markers. Neurodevelopment & neurodegeneration studies.
Human Cortical GABAergic Neurons 40HU-022 Functional GABAergic neurons; GAD67 & vGAT positive. Multi-cellular CNS models with inhibitory neurons.
Human Dopaminergic Neurons 40HU-002 Dopaminergic neurons (DA); TH & FoxA2 positive. Parkinson’s, Lewy body dementia, DA pathway research.
Human iPS Cell Line 30HU-002 Feeder-free, integration-free iPSCs; pluripotency markers, normal karyotype. Differentiation into neurons, astrocytes, microglia, muscle, hepatocytes.
Human Motor Neurons 40HU-005 Functional motor neurons; HB9, ISL1, ChAT positive; mature spiking activity. ALS, neuromuscular & neurodegeneration models.
Human Neural Stem Cells 40HU-001 NSCs; Nestin, Pax6, Sox1 positive; multipotent. Intermediate for motor neuron & astrocyte differentiation.
Human Sensory Neurons 40HU-013 Functional sensory neurons; Peripherin & BRN3A positive. Chronic pain, drug development, neurotoxicity assays.
Human Skeletal Muscle Myoblasts 40HU-176 Express MyoD & Desmin; differentiate into MHC/Dystrophin/Myog+ myotubes. Duchenne/Becker muscular dystrophy, myogenesis studies.
Human Glutamatergic Neurons (GFP-labelled) 40HU-014-GFP Glutamatergic neurons; VGLUT2, MAP2, TUJ1 positive; active and maturing. Neuronal function, drug responses, neurotoxicity, high-content screening.

Enhance Your Research with Disease-Relevant iPSC Models

Strengthen your studies by integrating patient-derived disease models alongside healthy donor lines. These genetically defined iPSCs provide meaningful pathological context, enabling clearer comparisons, deeper mechanistic insights, and more predictive translational outcomes.

Enhance Your Workflow with Recommended Accessory Products

Pair your selected iPSC models with high-quality tools for reproducible and physiologically relevant results:

Why Choose Tebubio & iXCells

  • Fast, reliable, and ready to use, get iPSC products integrated into your workflow immediately.

  • Optimised protocols ensure consistency, scalability, and speed across all experiments.

  • Flexible iPSC options, off-the-shelf products from multiple donor types to suit diverse studies.

  • Maximum reliability: feeder-free, integration-free systems for reproducible results.

Start Building Predictive, Human-Relevant In-Vitro Models Today

From disease modelling to high-content screening and drug discovery, Tebubio and the iPSCore™ platform provide the human-relevant reliability your research demands.

  • Reference

    Figure 1: Courtesy of iXCells, your trusted supplier for iPSCs.

Need Expert Guidance for Your iPSC Models?

Our scientific experts can help you identify the most suitable human iPSC models and complementary tools for your research goals.

Get tailored advice to optimise your workflows, ensure reproducibility, and accelerate your discoveries.