Scientific Library
DDI studies: New TransiPort cells for OATP1A2 and OATP2B1 transporters
Membrane transporters can have clinically relevant effects on the pharmacokinetics and pharmacodynamics of a drug in various organs and tissues by controlling its absorption, distribution and elimination.
How to get rid of fibroblastic contaminating cells?
Tissue culture for Primary cell isolation are often jeopardized by the outgrowth of contaminating fibroblasts. As fibroblasts usually grow at a much faster rate compared to the target
Fully licensed SLC cell lines for FDA and EMA recommended transporters
In a previous post, we introduced our Ready-to-use cellular models for SLC assays by GenoMembrane.
These cell lines transiently express the current FDA and EMA recommended SLC