BODIPY TMR PI(3 4 5)P3 - 50 ug

BODIPY TMR PI(3 4 5)P3 (BODIPY TMR Phosphatidylinositol 3 4 5-trisphosphate) is a water soluble analog of PI(3 4 5)P3 (PIP3) labeled with the orange fluorophore Bodipy®-TMR at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2. Bulk discounts available please email echelon@echelon-inc.com for information. Powered by Bioz See more details on Bioz