Biotinylated Anti-PtdIns(4 5)P2 IgM - 250 ug

Purified Anti-PtdIns(4 5)P2 monoclonal antibody conjugated with biotin.Subclass: IgMSource: MouseClone: 2C11Applications: ELISA Immunofluorescence Protein-Lipid Overlay (PIP Strip) Flow CytometryPhosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4 5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PIP3. Powered by Bioz See more details on BiozSelected Publications:1) Hoek K. L. P. Antony et al. (2006). "Transitional B cell fate is associated with developmental stage-specific regulation of diacylglycerol and calcium signaling upon B cell receptor engagement." J Immunol 177(8): 5405-13.2) Antony P.