Autotaxin Enzyme active - 25 ug

Echelon's Autotaxin enzyme is a secreted human β isoform (teratocarcinoma derived) of autotaxin with C-terminal 6-His tagThe secreted human β isoform (teratocarcinoma derived) autotaxin with C-terminal 6-His tag was expressed in Sf9 cells and purified using nickel-NTA chromatography. The enzyme is supplied lyophilized (Contains dextrose Hepes trehalose and Tween 20) and is tested for activity before release. For lot specific activity request Certificate of Analysis (COA)Autotaxin also known as ATX eENPP2 lysophospholipase D phosphodiesterase 1α and plasma cell glycoprotein-1 is a secreted glycoprotein that is widely expressed with high levels in the serum. Via its lysophospholipase D (lysoPLD) activity autotaxin hydrolyzes lysophosphatidylcholine (LPC) to generate the phospholipid growth factor lysophosphatidic acid (LPA). The enzyme’s same activity hydrolyzes sphingosylphosphorylcholine (SPC) to form sphinosine1-phosphate (S1P). Powered by Bioz See more details on Bioz