AS604850 (PI3-K gamma Inhibitor 2) - 5 mg

5-(2 2-Difluoro-benzo[1 3]dioxol-5-ylmethylene)-thiazolidine-2 4-dione (AS604850) is an inhibitor of PI 3-Kγ with an IC50 = 250 nM. AS604850 is selective for the γ-isoform (IC50: PI 3-Kα = 4.5 μM PI 3-Kβ PI 3-Kδ > 20 μM) and shows no notable activity against a wide array of protein kinases at 1 μM.References Powered by Bioz See more details on Bioz1) M. Camps et al. "Blockade of PI3Kg suppresses joint inflammation and damage in mouse models of rheumatoid arthritis" Nature Medicine 2005 11 936-943.

Supplier Catalog Number

 B-0302

Shipping conditions

 Room temperature

Storage Temperature

 +4°C

Supplier name

 Echelon Biosciences
From
€159.00
Total €159.00

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