AS1949490 (SHIP2 Inhibitor) - 25 mg

AS1949490 is a potent selective SHIP2 inhibitor with IC50 of 0.62 uM for human which shows less effect on SHIP1 or no effects on some other types of intracellular phosphatases (such as PTEN synaptojanin and myotubularin). This compound also activates intracellular insulin signaling pathways in the liver and displays gluconeogensis regulation and antidiabetic effects.References Powered by Bioz See more details on BiozA. Suwa T. Yamanoto et al. "Discovery and functional characterization of a novel small molecule inhibitor of the intracellular phosphatase SHIP2" British Journal of Pharmacology 2009 158 879-88.