Ac-Lys-Gln-Lys-Leu-Arg-4-methoxy-2-naphthylamide - 5 mg

Molecular Weight: 869.08Salt Form: TFAPurity: >95%Sequence (3-letter): Ac-Lys-Gln-Lys-Leu-Arg-MbNASequence (1-letter): Ac-KQKLR-MbNAStorage: -20 °C or belowAc-KQKLR-MbNA is a fluorogenic substrate for Cathepsin S. Cathepsin S is a lysosomal cysteine protease with important roles in MHC Class II antigen presentation and nociception. Cathepsin S also cleaves several extracellular matrix proteins (laminin fibronectin elastin osteocalcin) and glycosaminoglycans (heparin sulfate chondroitin sulfate).Activity is quantified by release of free fluorescent 4-Methoxy-β-naphthylamine (4MβNA) which excites at 335-350 nm and emits at 410-440 nm