Ac-Leu-Glu-His-Asp-AFC (Caspase 9 Substrate) - 25 mg

CAS Number: 210345-03-2 Molecular Weight: 765.27 Salt Form: TFA Purity: >96% Sequence (3-letter): Ac-Leu-Glu-His-Asp-AFC Sequence (1-letter): Ac-LEHD-AFC Storage: -20 °C or belowAc-Leu-Glu-His-Asp-AFC is a fluorogenic substrate for caspase 9. Caspase 9 is a cysteine protease which acts as an initiating enzyme in apoptosis pathways. It activates Caspases 3 6 & 7.Activity is quantified by release of free fluorescent 7-amino-4-trifluoromethylcoumarin (AFC) which excites at 395-400 nm and emits at 495-505 nm.