Ac-Arg-Leu-Arg-AMC - 1 mg

CAS Number: 929903-87-7Molecular Weight: 642.7Salt Form: TFAPurity: >96%Sequence (3-letter): Ac-Arg-Leu-Arg-AMCSequence (1-letter): (Ac)RLR(AMC)Storage: -20 °C or belowAc-Arg-Leu-Arg-AMC is a fluorogenic peptide that is usually the substrate of choice for assaying activity of purified proteasomes. Some substrates with R-AMC bonds can be used for assaying trypsin-like activity. Ac-Arg-Leu-Arg-AMC has a low Km high specific activity and is cleaved exclusively at the Arg-AMC bond.Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.