5-Azacytidine - 250 mg

Activity: DNA hypomethylation agent . Function/Pharmacology: Specific inhibitor of DNA methyltransferase1. Incorporates into DNA and covalently reacts with and inhibits DNA methyltransferases. Induces demethylation and reactivation of silenced genes2. Increases stem cell reprogramming efficiency3. Induces cardiac differentiation of human mesenchymal stem cells by activating ERK4. Induces apoptosis in multiple myeloma cells via ATR-mediated DNA double strand breaks5. Cell permeable. Chemical Name: 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one