4A3-SCC-10 - 5 mg
The linker-degradable ionizable lipid (LDIL) 4A3-SCC-10 possesses superior endosomal escape and rapid mRNA release abilities thanks to its unique GSH-responsive cone-shaped architecture. Lipid nanoparticles (LNPs) of 4A3-SCC-10 showed improved mCherry mRNA delivery in livers by 87-fold compared to DLin-MC3-DMA in vivo. 4A3-SCC-10 also demonstrated improved mRNA delivery in vivo compared to its parent counterpart without a disulfide bond or control counterpart with a disulfide bond in the tail.
Supplier Catalog Number |
N-1430 |
|---|---|
Shipping conditions |
Room temperature |
Storage Temperature |
-20°C |
Supplier name |
Echelon Biosciences |
From
€280.00
Total
€280.00
In stock
- SKU
- P01185197::5 MG
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