3-Methyladenine - 50 mg

3-Methyladenine inhibits autophagy by blocking autophagosome formation via inhibition of type III phosphatidylinositol 3-kinases (PI-3K). It protects 1321N1 astrocytoma cells against pyocyanin and hydroxyphenazine-induced toxicity. Inhibition of autophagy by 3-MA leads to enhanced apoptosis induced by a variety of agents including celastrol, cisplatin and sorafenib in several different cell lines.

Supplier Catalog Number

AC1002

Shipping conditions

Cool pack

Storage Temperature

-20°C

Supplier name

LifeSensors

CAS Number

5142-23-4
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€234.00
Total €234.00

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Additional information

CAS Number: 5142-23-4
Application: Cell-based Assay