Human MGMT Methylation Assay - 1 box

The ASY470 assay is specifically designed for the quantitative analysis of the Exon 1 region of the MGMT gene, encompassing 14 CpG sites located at Chr10:129467230-129467322 (GRCh38). This assay delivers precise and reliable measurement of methylation levels, providing essential insights into the gene's epigenetic regulation. The methylation status of this MGMT region acts as a critical biomarker for assessing patient response to alkylating agents, such as temozolomide, particularly in the treatment of brain tumors like glioblastoma.