Scientific Library
Post-Translational Modifications (PTM) of Tubulin
In this post, I'd like to take a look at the current understanding of tubulin PTMs, that include tyrosination/detyrosination, Δ2-tubulin formation, acetylation, phosphorylation, ubiquitination, glutamylation,
3 functional assays to investigate actin dynamics
Today, I'd like to give you an overview about methods in actin research with validated R&DÂ products and kits which will allow you to measure binding to actin and effects on the polymerisation dynamics
New effective anti-Human IFN neutralizing antibody
PBL Assay Sciences offer a new monoclonal antibody to neutralize Human Interferon (IFN) activity,
Human IFN ELISA test: unrivaled sensitivity and global IFN alpha detection
PBL assay specializes in the development of IFN related research Tools. One of their most appreciated assay kit by the IFN research community is the ELISA test kit for all Human IFN Alpha subtypes (41115
New - 4 Unique IFN Neutralizing reagents
PBL Assay Science, the specialists of Interferon related quality reagents, have just released 4 new unique products to be used in neutralization assays. I am pleased to introduce them in this post, in
Cell signalling: How to easily detect mono- and poly-Ub target proteins
How to make Post Translational Modification characterization easier
Signal-Seeker assays (Cytoskeleton Inc.) provide researchers with the most comprehensive reagents enabling highly sensitive and specific detection of the key Post Translational Modifications (PTMs)
Cell signalling studies: Tips for selecting the best Small G Protein activation assay
Small GTP-binding proteins such as Rho and Ras GTPase family members are involved in regulating cell signalling pathways and impact a wide range of cellular processes, functions, and morphology. In this
Therapeutic Target - Ubiquitin-Proteasome system: What about tubulin?
The ubiquitin-proteasome system (UPS) is a well-characterized protein degradation system in cells whose dysfunction is implicated in many diseases, including neurodegeneration and cancer1,2. Major UPS
Powerful and reliable solutions to decipher Actin Dynamics
As is well known, the actin cytoskeleton is a highly dynamic structure, involved in a large number of cellular processes, including muscle contraction, lamellopodial extrusion, cell locomotion, cytokinesis,