AP39 - 25 mg

Activity: Mitochondria-targeted hydrogen sulfide donor . Function/Pharmacology: Mitochondrially targeted hydrogen sulfide donor. At lower concentrations (30 -100 nM), it acts as an electron donor and stimulator of mitochondrial electron transport and ATP production. AP39 displayed antioxidant and cytoprotective effects in oxidatively stressed endothelial cells.1 It displayed protective effects in various pathological states including renal injury2,3, Alzheimer's4, ischemia5, and reperfusion injury6. Improves outcomes in subnormothermic organ preservation models.7,8 Chemical Name: (10-Oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy)decyl)triphenylphosphonium bromide