Anti-ABCB8 (RABBIT) Antibody - - 100 µL

This antibody is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI) and is suitable for Cancer Research and drug resistance. ABCB8 is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI). It has been found that ABC transporters are involved in mulitdrug resistance through their ability to control the presence of drugs in cells. Multidrug resistance is currently being looked at in particular reference to cancer that is resistant to treatment. ABCB8 seems to have particularly high resistance rates in renal cancer and cancer of the central nervous system. Another significant aspect of ABCB8 is that it is a mitochondrial transporter. There are very few ABC transporters localized to the mitochondria which implies information about them could be extremely important. ABCB8 may also be localized to other parts of the cell which are yet to be determined. Anti-A