Anti-ABCB5 (RABBIT) Antibody - - 25 µL

This antibody is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Anti-ABCB5 Antibody is a ATP-Binding Cassette protein. ABCB5 is a novel member of the human P-glycoprotein family.  It functions as a determinant of membrane potential and regulator of cell fusion in physiologic skin progenitor cells.  Cell fusion is thought to contribute to tissue differentiation.  ABCB5 is predominantly expressed in melanoma cells and is a novel molecular marker for a distinct subset of chemoresistant stem cell phenotype-expressing tumor cells among human epidermal melanocytes.  ABCB5 is a rhodamine efflux transporter.  This antibody product is intended to be used to confirm cellular localization and expression level of ABCB5. ABCB5 antibody is ideal for Cancer and Signal Transduction research.