Allopregnanolone - 5 mg

Activity: GABA-A positive allosteric modulator . Function/Pharmacology: Endogenous neurosteroid which acts as a positive allosteric modulator of GABAA receptors.1,2 Recently FDA approved (Brexanolone) for postpartum depression.3 Inhibits TLR4 receptor activation and inflammatory signaling in macrophages and brain.4 Inhibits glutamate release5 and displays neuroprotective effects in various animal models6. Chemical Name: (3α,5α)-3-Hydroxy-pregnan-20-one