AI-3 - 25 mg

Activity: ARE activator . Function/Pharmacology: Activator of antioxidant response element (ARE) which induces cytoprotective genes in human cells. It alkylates Keap1 at Cys151 and is reactive toward additional cysteines at higher concentrations. Disrupts Nrf2/Keap1 and Keap1/Cul3 interactions and stabilizes Nrf2. Activates ARE in an Nrf2 and PI 3-kinase dependent manner. Cell permeable and active in vivo. Chemical Name: 1-Chloro-6,7-dihydro-6,6-dimethyl-3-(methylsulfonyl)-benzo[c]thiophen-4(5H)-one

Supplier Catalog Number

 10-1497

Shipping conditions

 Room temperature

Storage Temperature

 -20°C

Supplier name

 Focus Biomolecules

CAS Number

 882288-28-0
From
€420.00
Total €420.00

No surprise after checkout. All fees included

Your satisfaction first: door delivery with guaranteed replacement

Dedicated Scientific Support to select & use

Additional information

CAS Number: 882288-28-0