AG-1517 · HCl - 5 mg

Activity: Tyrosine kinase inhibitor . Function/Pharmacology: An ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFRK), with an IC50 of 25 pM. Inhibits other tyrosine kinases at micromolar or higher concentrations. It selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression and oncogenic transformation1. Inhibits the growth of a number of cancer cell lines2. An extremely useful tool for exploring EGF-mediated cellular signaling3. Chemical Name: 4-(3-Bromoanilino)-6,7-dimethoxyquinazoline hydrochloride

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 10-1377

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Supplier name

 Focus Biomolecules

CAS Number

 153436-54-5
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CAS Number: 153436-54-5