7,8-Dihydroxyflavone - 500 mg

Activity: TrkB agonist/neurotrophic . Function/Pharmacology: A selective TrkB agonist (Kd=320 nM) with potent neurotrophic activity.1,2 Significantly improves motor deficits, ameliorates brain atrophy and extends survival in the well-characterized N171-82Q Huntington’s disease mouse model.3 Post-traumatic brain injury-treatment promotes neurogenesis in the hippocampus in a mouse model.4 Improves motor performance and motor neuronal survival in an ALS mouse model.5 Chemical Name: 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one