TAME HCl - 100 mg

Datasheet
Inhibits the ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C) by inhibiting binding and activation by the APC activators Cdc20 and Cdh1. TAME inhibits cyclin proteolysis in Xenopus extracts (IC50 = 12 µM) and inhibits Cdc20 association with APC at 200 µM. It stabilizes cyclin B1 by prematurely terminating ubiquitination. Substrate for trypsin, thrombin, plasmin, and other proteases.

Supplier Catalog Number

 SI9840

Shipping conditions

 Cool pack

Storage Temperature

 -20°C

Supplier name

 LifeSensors

CAS Number

 1784-03-8
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SEK 3,102.00
Total SEK 3,102.00

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Additional information

CAS Number: 1784-03-8
Application: Cell-based Assay