Luciferase is the general term given to a class of oxidative enzymes that catalyze reactions that give off light, a process known as bio-luminescence (Fig. 1). In biology,
Page 5 - Scientific Library
Article
3 new mitochondrial research reagents
October 27, 2016
Research tools aimed at exploring mitochondria are becoming more and more popular and cover multiple experimental applications. They go from primary antibodies validated for immuno-assays (see
Article
Screen for inhibitors of PD-1 signalling with a complete cellular assay system
October 28, 2016
Immunotherapy represents a field in Drug Discovery which is quickly developing and leading to significant progress in treatments of a number of diseases, especially cancer. The approach is based on inducing,
Application Note
New - Continued use immunotherapy cell line expressing recombinant PD-1
February 03, 2017
PD-1/NFAT-Luciferase reporter jurkat cell line used to monitor the T cell response inhibition via PD-1 interacting with PD-L1/PD-L2
PD-1 / NFAT Reporter - Jurkat Cell Line
The PD-1 reporter cell line is
Article
3D Cell culture: Innovative cell culture devices for more predictive 3D models
April 05, 2017
One of the biggest challenges as a researcher in life sciences, is to obtain proof of concept the more predictive as possible. To help you to reach your objectives, many innovative tools are being developed
Article
Cell Signalling: MAP Kinase Signalling with phospho ELISA test
April 27, 2017
The mitogen-activated protein kinase (MAPK) signaling pathway is activated by a number of extra and intracellular stimuli including cytokines, growth factors, and hormones as well as stressors such as
Article
Sekisui XenoTech Awarded Cryopreservation Patent for Cryostax single freeze hepatocytes
May 12, 2017
Sekisui XenoTech has just been issued U.S. Patent No. 9,642,355 for the “cryopreservation of cells and subcellular fractions,” specifically related to Sekisui XenoTech’s CryostaX® test systems. This hepatocyte
Article
Cell Signalling: Ras-Raf-MEK-ERK pathway research tools
July 07, 2017
The Ras-Raf-MEK-ERK Pathway is an important cell signalling route with many implications for cancer biology and therapeutic development. Dis-regulation of some of this pathway's proteins expression and
Article
cAMP signals visualized in live human pancreatic primary cells
July 21, 2017
In a recent publication, researchers from the University of Miami Miller School of Medicine (USA) describe that Serotonin released by human beta cell inhibits glucagon secretion by alpha cells. They demonstrated
Article
ADME-Tox: liver fractions with High Aldehyde Oxidase and Xanthine Oxidase Activity
September 08, 2017
Sekisui XenoTech has just established a method for high Aldehyde Oxidase and Xanthine Oxidase activity in pooled Human liver test systems.
These new test systems (Pooled Human Liver S9 and cytosol) have