Scientific Library
TUBEs: study M1 (linear) polyubiquitylated proteins
Traditional methods to detect and purify poly-ubiquitinated proteins require either anti-ubiquitin antibodies or Ubiquitin Binding Associated domains (UBAs). Most of the current methods display rather
New Polyethylene Glycols (PEG) as versatile biochemical linkers
Polyethylene Glycols (aka. PEGs) are biologically inert, non-immunogenic, and hydrophilic molecules. These properties make them very attractive for research and drug discovery applications (ex. Antibody-Drug
3D Cell culture: Innovative cell culture devices for more predictive 3D models
One of the biggest challenges as a researcher in life sciences, is to obtain proof of concept the more predictive as possible. To help you to reach your objectives, many innovative tools are being developed
3D cell culture Biochip - versatile for more physiological applications
By mimicking in-vivo environments, 3D cell culture models appear nowadays as the best in-vitro study model to work in an in-vivo like study model and to obtain more physiologically relevant data and proof
3 new types of Gastrointestinal (GI) Epithelial primary cells
Gastrointestinal (GI) primary cells represent a powerful approach for the in vitro study of the physiopathology of this unique tissue. Researchers have now identified intimate interactions between GI
AIM Biochips - 3D cell culture platform for Immunotherapy and T Cell therapy studies
As mentioned in a previous post the DAX Biochips from AIM Biotech are an innovative and versatile microfluidic platform, allowing researchers to more easily develop 3D cell culture models, to work as close
Neurons, Astrocytes, Microglia: High Quality primary cells source
In the field of neurosciences, increasing research is being undertaken on neurodegenerative disorders like Parkinson’s and Alzheimer’s diseases, as well as on nerve injury and regeneration. One of the
How to obtain reliable DNA and RNA quantitation
The iQuant kits developped by ABP Bioprobes provide accurate quantitation of DNA and RNA with a wide range including high sensitivity. They are useful for NGS applications, qPCR analysis, and in vitro
Pre-screened endothelial cells validated for signalling biomarkers
Working with primary cells can be tricky at times. It's always best to know in advance what essential markers your cell model does express not to waste time and efforts in working with an inappropriate
VU-1: The most efficient monoclonal Antibody for ubiquitin detection
In the field of anti-ubiquitin antibodies many solutions are available on the market. But LifeSensors, a company specialized in Ubiquitin research field, have developped a monoclonal antibody called VU-1
Smooth Muscle Cells: Ready-to-Use, QC tested Specialized Media
Producing specialized media for specific primary cell types may be best outsourced to specialized manufacturers in order to obtain optimal results for this type of cell culture, more tricky than standard
Primary cells: ready-to-use, QC tested media
In a previous post, I introduced a complete panel of ready-to-use specialized media for smooth muscle primary cells culture. Produced by Cell Applications, a GMP certified manufacturer of primary cells