PTC-209 - 5 mg

Treatment of cells with PTC-209 leads to the selective reduction in the levels of BMI-1 protein (Kreso, van Galen et al. 2014). BMI-1 is a component of the polycomb PRC complex and interacts directly with the E3 ligase RING1A and/or RING2. The PRC complex mediates monoubiquitylation of histone H2A on Lys-119 and is involved in chromatin remodeling and repression of gene expression.

Supplier Catalog Number

SI9855

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Cool pack

Storage Temperature

-20°C

Supplier name

LifeSensors

CAS Number

1217022-63-3
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SEK 3,465.00
Total SEK 3,465.00

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Additional information

CAS Number: 1217022-63-3
Application: Cell-based Assay