Scientific Library
Human oligodendrocyte MO3.13 cells & Globoid cell leukodystrophy
In this paper (Role of extracellular calcium and mitochondrial oxygen species in psychosine-induced oligodendrocyte cell death), Voccoli et al. used Human oligodendrocyte MO3.13 cells to study Globoid
Why is the hCMEC/D3 cell line a robust in vitro BBB model?
The Blood-Brain Barrier (BBB) affects the development of drugs for all pathologies (brain exposure to drugs, side effects...). In the early phases of drug development, there is a strong need for stable
5 multicolour flow cytometry reagents for immunophenotyping
Multicolour fluorochrome reagents have spurred researchers' capacity to analyze cell populations and to isolate cell subsets by flow cytometry. In this post, let's take at look at the advantages of
2 new validated anti-PGP 9.5 antibodies for neuroscience research
Protein Gene Product 9.5 (PGP 9.5) is an abundant cytoplasmic neuron and neuroendocrine-cell specific protein. Over the years, this deubiquitinating enzyme (a.k.a. Ubiquitin Carboxy-terminal Hydrolase
Lympholyte®: The ideal tool for simple and viable lymphocytes isolation
High quality isolation of lymphocytes is a key step in many in vitro research programs covering immunology, infectious diseases and oncology. To simplify this step, CEDARLANE® have developed an efficient
Production of eGFP mRNA Labeled with Fluorophore for Tracking of Delivery and Expression
Our Contract Research Services (CRS) team developed eGFP mRNA labeled with a fluorophore to monitor its delivery and expression efficiency in cells.
RNA Production Platform and the Associated Solutions Facilitate the Development of RNA-Based Vaccines
RNA vaccines have shown their full potential in the Covid-19 pandemic. The application of these technologies for the treatment of cancers represents a significant promise, but clinical effectiveness remains
Standardized 3D Spheroid Systems Facilitate Drug Screening and Biomarker Identification with High Relevance for Cancer Drug Discovery
Our customer needed to investigate whether modulating key culture parameters could improve the predictivity of their colorectal cancer cell-based methodology used to select CDK8 inhibitors and/or identify
Multiplex Antibody Array for Protein Profiling and Biostatistical Analysis to Assess the Effect of Oxaliplatin on Mouse Fibrosarcoma Cell Line
Oxaliplatin (OXA) is a chemotherapeutic drug which causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin is known as immunogenic cell death
Development of Cost Effective and Robust 3D Colorectal Cancer Models for Physiological Drug Response Analysis
Our customer needed to obtain in vivo like responses to drug treatment, through monitoring parameters such as gene expression, biomarker analysis, cellular viability, invasion capability.
Lipid Nanoparticles (LNP): The New Cargo for Drug Delivery
Explore how to optimize Lipid Nanoparticules (LNP) for mRNA delivery for druf development. This study highlights key formulation parameters: buffer composition, lipid selection; crucial for enhancing transfection
Unlock the Full Potential of Your Protein Production
Flexible Protein Production Services for Custom Expression & Purification
Tebubio’s Protein Production Platform offers custom expression strategies using bacterial & mammalian (HEK293) systems. Our adaptable