Page 15 - Scientific Library
Focus on the Notch signaling pathway...
The Notch signaling pathway plays a vital role in the regulation of asymmetric cell division, cell fate specification and proliferation. Mammals possess 4 different Notch receptors, referred to as Notch1,
5 reliable research tools to study ERG, USP9X and DUB inhibitor in prostate cancer
In a recent paper published in PNAS, Wang et al. show that the inhibition of the deubiquitinase USP9x by the small molecule WP-1130 is able to induce degradation of the transcription factor E-twenty-six
Return of SIRT1 deacetylase - Why is SIRT1 so attractive in Drug discovery and Stem cell research?
1 simple way to rapidly quantify Collagen: Sircol Collagen Assay
Collagen is a structural protein expressed in mammalian tissues (ex. skin, muscles, tendons, ligaments, cartilages, blood vessels...). Together with Elastin and Keratin, Collagen fibres give connective
Proteome, secretome, kinome… What’s it all about?
Proteome is referenced as the result of expression of the whole genome. With the recent developments of genomics, one could consider that this analysis is enough to decipher any biological mechanism...