TAME HCl - 100 mg

Inhibits the ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C) by inhibiting binding and activation by the APC activators Cdc20 and Cdh1. TAME inhibits cyclin proteolysis in Xenopus extracts (IC50 = 12 µM) and inhibits Cdc20 association with APC at 200 µM. It stabilizes cyclin B1 by prematurely terminating ubiquitination. Substrate for trypsin, thrombin, plasmin, and other proteases.

Supplier Catalog Number

SI9840

Shipping conditions

Cool pack

Storage Temperature

-20°C

Supplier name

LifeSensors

CAS Number

1784-03-8
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NOK 2,820.00
Total NOK 2,820.00

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Additional information

CAS Number: 1784-03-8
Application: Cell-based Assay