Spautin 1 - 5 mg

Spautin 1 inhibits USP10 and USP13 with IC50’s of 0.6 μM and 0.7 μM, respectively. These deubiquitylases target the Beclin-1 subunit and promote degradation of Vps34-PI3 kinase complexes. Its effect on autophagy is Beclin-independent. Spautin induces apoptosis of cancer cells under starvation conditions.

Supplier Catalog Number

SI9644

Shipping conditions

Cool pack

Storage Temperature

-20°C

Supplier name

LifeSensors

CAS Number

126288-28-7
From
NOK 1,710.00
Total NOK 1,710.00

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Additional information

CAS Number: 126288-28-7
Application: Cell-based Assay