Nutlin-3 - 5 mg
Cis-imidazoline analog that inhibits the interaction between p53 and its negative regulator MDM2 (IC50 = 0.09 μM). It induces the expression of p53-regulated genes and exhibits potent antiproliferative activity in cells with functional p53, but not in cells with mutated p53. Nutlin-3 also inhibits the growth of human tumor xenografts in nude mice by 90% at a dose of 200 mg/kg.
Supplier Catalog Number |
SI9870 |
|---|---|
Shipping conditions |
Cool pack |
Storage Temperature |
-20°C |
Supplier name |
LifeSensors |
CAS Number |
548472-68-0 |
From
NOKÂ 3,500.00
Total
NOKÂ 3,500.00
In stock
- SKU
- P00199770::5 MG
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Additional information
CAS Number: 548472-68-0
Application: Cell-based Assay
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