ML323 - 5 mg
ML323 binds to the complex of USP1-UAF1 resulting in the inhibition of USP1 deubiquitylase activity (Liang, Dexheimer et al. 2014). The IC50 is reported to be 76 nM against Ub-Rho110 and 174 nM against K63-linked diubiquitin. Inhibition is reversible and exhibits mixed-mode kinetics. ML323 showed little or no inhibitory activity against a collection of DUBs including USPs 2, 5, 7, 8, 10, 11, 14, and 21, UCH-L1 and UCH-L3, and SenP1.
Supplier Catalog Number |
SI9634 |
|---|---|
Shipping conditions |
Cool pack |
Storage Temperature |
-20°C |
Supplier name |
LifeSensors |
CAS Number |
1572414-83-5 |
From
NOKÂ 3,270.00
Total
NOKÂ 3,270.00
In stock
- SKU
- P00199738::5 MG
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Additional information
CAS Number: 1572414-83-5
Application: In vitro Assay
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