LDN-57444, DUB inhibitor - 10 mg
LDN-57444 is a cell permeable ubiquitin C-terminal hydrolase (UCH-L1) inhibitor (Ki=0.4 µM) with approximately 28-fold greater selectivity over UCH-L3. Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis and causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. LDN-57444 is a useful tool to study UCH-L1 in different pathological conditions such as cancer and neurodegeneration.
Supplier Catalog Number |
SI9639 |
|---|---|
Shipping conditions |
Cool pack |
Storage Temperature |
-20°C |
Supplier name |
LifeSensors |
CAS Number |
668467-91-2 |
From
NOKÂ 2,550.00
Total
NOKÂ 2,550.00
In stock
- SKU
- P00199739::10 mg
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Additional information
CAS Number: 668467-91-2
Application: Cell-based Assay
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