Anti-Human CD314 (NKG2D) PE - 25 tests

The 1D11 monoclonal antibody specifically binds to human CD314 (NKG2D), a transmembrane C-type lectin-like receptor. CD314 recognizes proteins that appear on the surface of NK cells and T cell subtypes. CD314 is a major recognition receptor for the detection and elimination of transformed and infected cells as its ligands are induced during cellular stress. The 1D11 antibody is reported to block the binding of soluble MICA to gamma delta TCR T cell clones and inhibit lysis by these cells.