Anti-Human CD23 PE - 25 tests

The EBVCS-5 monclonal antibody specifically binds to human CD23, a type II membrane glycoclone protein that is also called FC epsilon RII or the the low-affinity IgE receptor. It belongs to the C-type lectin structural family and plays a role in the regulation of IgE synthesis and IgE mediated activities. In addition to binding IgE, also exerts a number of IgE independent activities, such as promoting the activation and differentiation of B-cells and stimulating the release of pro-inflammatory cytokines from monocytes. CD23 is expressed on mature B cells, follicular mantle B cells, and a subset of T cells.