Anti-ASAP1 (RABBIT) Antibody - - 100 µg

This antibody is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI). ASAP1 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1) is a Protein Coding gene. This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. ASAP1 may function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity) and plays a role in ciliogenesis. Anti-ASAP1 is useful for researchers interested in GTPase activities and EGFR1 Signaling Pathway.