Anti-Aquaporin 2 (RABBIT) Antibody - - 100 µg

Aquaporins are membrane proteins that serve in the transfer of water and small solutes across cellular membranes. One such aquaporin, aquaporin-2 (AQP2) is located in the kidney collecting tubule and plays a critical role in water reabsorption. AQP2 is mainly localized in intracellular vesicles but upon stimulation with anti-diuretic hormone (ADH), AQP2 is translocated to the apical plasma membrane by exocytic fusion of AQP2-bearing vesicles. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus.