ABC294640 (SPHK2 Inhibitor) - 5 mg

ABC294640 (Opaganib) is an orally bioavailable selective inhibitor of sphingosine kinase 2 (SPHK2 or SK2). Sphingosine kinases phosphorylate sphingosine producing the bioactive lipid sphingosine 1-phosphate which has roles in cell proliferation and cell motility. Sphingosine kinases are up-regulated in numerous forms of cancer and ABC294640 alone or in combination has been shown to suppress growth in kidney breast liver colon and lung cancer cell lines.References Powered by Bioz See more details on Bioz