1-EBIO - 50 mg

Activity: K+ channel activator; Cardiomyocyte differentiation . Function/Pharmacology: A direct activator of small-conductance Ca2+-activated K+ channels (SK) which dose-dependently relaxes rat mesenteric vessels.1 Reverses ischemia-induced cognitive impairment2 and displays neuroprotective effects in ischemia-induced neuronal cell death3. Induces embryonic stem cell differentiation into cardiomyocytes and enrichment of pacemaker-like cells.4 Induces production of superoxide and hydrogen peroxide in neutrophils with subsequent apoptosis.5 Chemical Name: 1-Ethyl-1,3-dihydro-2H-benzimidazol-2-one