Scientific Library
MitoTools: Mitochondrial research has never been so easy
Involved in many physiological processes (apoptosis, aging, cell signalling..) and numerous diseases (cardiovascular disorders, to cancer and neuro-degenerative diseases…), Mitochondria have become more
3 colour Live Cell Imaging - Actin, Tubulin and DNA
Following on from the popular SiR-Probes, earlier this year Spirochrome introduced new SPY probes, as presented in this post.
Take a few minues to watch this video of the SPYâ„¢ Actin, Tubulin and DNA
New Flipper-TR probes - easily measure membrane tension in cells
Despite its importance in the regulation of many cellular processes, membrane tension is still complicated to measure. And despite valuable insights, the techniques currently available remain complex and
New cutting-edge SPY labelling probes
With the great success of the SIR-probes for efficient labeling of the cell Cytoskeleton, DNA and Lysosome, Spirochrome have just launched a series of 10 new live cell fluorescent tools : The SPYTM probes
What mitochondria related diseases?
All human and living beings have mitochondria. These are tiny cellular organisms present in nearly every cell of an individual. They are located more precisely inside the cells, in their nucleus. The main
Senescent cells prevent muscle regeneration
Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration
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In their latest publication in Nature, Dr. Moiseeva et.al., studied cellular senescence in skeletal muscle, carrying
Mitochondria-Lysosome Contacts in Neurogenetic Diseases
Mitochondrial Dynamics and Mitochondria-Lysosome Contacts in Neurogenetic Diseases
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In an article published in frontiers in Neuroscience, with the aim to study cellular phenotypes in fibroblasts from
Understanding cellular senescence and oxygen consumption rate
Understanding cellular senescence and oxygen consumption rate
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A recent paper published in Science reported a 50% reduction in mortality and improved immune response in old mice infected with SARS-CoV-2
Relationship between antitumor effects and active oxygen
Relationship between antitumor effects and active oxygen
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ROS (Reactive oxygen species) are highly reactive oxygen species mainly generated during the ATP synthesis process in mitochondria. While it is
Revolutionising Live Cell Imaging: Leveraging Novel Targeting Tools to Unlock New Frontiers in Cellular Research
The development of new probes marks significant progress in live-cell imaging. Peroxi_SPY555 and Peroxi_SPY650 are the first small-molecule probes designed specifically for peroxisome labelling, avoiding
Unveiling the Next Generation of Actin Imaging
Advancing Live-Cell Actin Imaging with Spirochrome New Products
Actin cytoskeleton imaging is a cornerstone of cellular biology, playing a pivotal role in understanding cell motility, morphology, and
Alzheimer’s Amyloid-β Accelerates Cell Senescence and Suppresses SIRT1 in Human Neural Stem Cells
In this blog, discover three assay kits developed by our partner Dojindo to accurately quantify and detect SA-β-Gal activity, and to explore a broad range of cellular processes linked to senescence.