Scientific Library
How to easily visualize and quantify cellular senescence
Due to its involvement in many cellular processes such as normal ageing, tumor suppression, chronic diseases and many more, cellular senescence has gained increasing attention since its first description
How to make Post Translational Modification characterization easier
Signal-Seeker assays (Cytoskeleton Inc.) provide researchers with the most comprehensive reagents enabling highly sensitive and specific detection of the
Cell-Based ELISA for in-cell protein phosphorylation and expression profile detection
Cell-Based ELISA tests now enable precise measurement of the phosphorylation status or expression profiles of target proteins (biomarkers) in whole cells. In this post, a review of high performing cell-based assays is made.
Interestingly, the experimental design is simple and is based on 3 steps:
- Plate
- Treat and fix your cells of interest (adherent or in suspension)
- Detect the target proteins with the optimized reagents provided in the kit (450 nm colorimetric detection)
These Colorimetric Cell-Based ELISA Kits enable the detection of various target proteins (biomarkers). Some references also enable the precise measurement of the phosphorylation status of proteins of interest. They can easily
Neurons, Astrocytes, Microglia: High Quality primary cells source
In the field of neurosciences, increasing research is being undertaken on neurodegenerative disorders like Parkinson’s and Alzheimer’s diseases, as well as on nerve injury and regeneration. One of the
How to obtain reliable DNA and RNA quantitation
The iQuant kits developped by ABP Bioprobes provide accurate quantitation of DNA and RNA with a wide range including high sensitivity. They are useful for NGS applications, qPCR analysis, and in
Consistent, scalable human iPSC-derived glutamatergic neurons and skeletal myocytes
As detailed in a separate post, bit.bio have developed a novel cellular reprogramming technology, opti-ox™
Tips and tricks to design and test qPCR primers - advanced procedure
Tips and tricks to design and test qPCR primers - advanced procedure
Design and test your own qPCR primers
- Find the NCBI Gene page for the gene you would like to
What is DNA?
DNA or deoxyribonucleic acid, and is the carrier molecule of hereditary genetic information.
DNA structure
DNA is a very long molecule, made up of a succession of nucleotides
What is the difference between Genetics and Genomics?
As similar as the two terms may seem, there is a fundamental difference between genetics and genomics.
Understanding this difference also means understanding their implications in cancer care, from
What type of Biological molecule is a DNA helicase?
There are several thousand types of different molecules in each cell (with some exceptions). These molecules are constantly changing and renewing themselves. Most of these molecules have a complex chemical
Choosing the Right Assay for PARP
Studying PARP family members is a high priority in cancer drug development
Are
Mitochondria-Lysosome Contacts in Neurogenetic Diseases
Mitochondrial Dynamics and Mitochondria-Lysosome Contacts in Neurogenetic Diseases
In an article published in frontiers in Neuroscience, with the aim to study cellular phenotypes