Intelliscreen™ Neuropathic Pain Ion Channel Mini-Library - 1 library

Activity: Comprises 12 inhibitors of various ion channels involved in pain transmission . Function/Pharmacology: Neuropathic pain is caused by damage or dysfunction to peripheral or central nervous system nerve fibers and is frequently chronic in nature. Persistent increased excitability and spontaneous activity in neurons leads to chronic pain that is difficult to treat. As the perception of pain is frequently transmitted via the activation of various ion channels, pharmacological modulation of these channels offers great therapeutic potential. Chemical Name: null