Page 10 - Scientific Library
Recent advances in Stem Cell culture: Encapsulated Stembeads growth factors
During my daily discussions with researchers involved in in vitro iPS and Embryonic Stem cell cultures, I am always amazed by the passion that drives them. However, the more I go in depth with
Primary cell sourcing: Cryopreserved Human Adult Sebocytes
Sebocytes are emerging cellular models to study skin biology but also to design new compounds to regulate acne, seborrhoea and other sebaceous gland-related diseases. Easy access to cryopreserved and well-qualified
Modulate hepatic inflammation
Kupffer cells are macrophages endogenous to the liver which have the ability to modulate hepatic inflammation and injury associated with various pathophysiologies and toxicities. Pro-inflammatory cytokines
Human Primary Sebocyte assay for compound testing on lipid metabolism
Sebocytes belong to the epidermal ecosystem together with hair follicules or in sebaceous glands. Sebocytes play a key role in skin health by producing sebum. These cells are now at the center of researchers'
Cytokines and growth factors in Bone biology
Bones are rigid organs that constitute part of the endoskeleton of vertebrates. They support and protect the various organs of the body, produce red and white blood cells and store minerals.
EndoG and ATM cell cycle checkpoint in Leukemogenesis
In a recent publication, Gole B. and Baumann C. demonstrate the role of the apoptotic nuclease EndoG in Mixed-Lineage Leukemia breakpoint cluster region (MLLbcr) destabilisation leading to MLL gene rearrangements
FAQs on feeder cells for optimal human iPSC culture
Human Newborn Foreskin Fibroblasts (NuFF cells) are genuine feeder cells for Stem cell research. Mitotically inactive NuFF cells (by irradiation or Mitomycin C chemical treatment) can
ATM or DNA-PKcs inhibitors synthetically lethal in BRCA- cells
Several lines of evidence show that synthetic lethal interactions targeting DNA repair pathways may have clinical applications in cancer therapy. In a recent paper, Albarakati et al. demonstrate
Tips for Optimizing Cell Culture Conditions with Hydrogels
In a previous post on Cellular Matrices for Translational Research, I introduced HyStem hydrogels. In order to engineer
Tumor growth and metastasis monitored in vivo
In vivo monitoring of tumor growth and metastasis provides a powerful means for studying cancer properties and development of effective therapies. Mouse models created with tumor xenografts, resulting