(R)-PFI-2 HCl - 5 mg

Activity: Methyltransferase SETD7 inhibitor . Function/Pharmacology: Potent (IC50 = 2nM) and selective SAM-dependent inhibitor of the lysine methyltransferase SETD7.1 It alters Hippo pathway signaling in MCF7 cells by altering YAP nuclear localization in a SETD7-dependent manner. Chemical Name: (1R)-1-[[3-(Trifluoromethyl)phenyl]methyl]-2-oxo-2-(1-pyrrolidinyl)ethyl-1,2,3,4-tetrahydro-6-isoquinolinesulfonamide hydrochloride

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10-4033

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Storage Temperature

-20°C

Supplier name

Focus Biomolecules

CAS Number

1627607-87-7
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CAS Number: 1627607-87-7