Advanced LNP Encapsulation Services

At Tebubio, we help researchers and biotech innovators turn promising molecules into therapeutic realities.

Our lipid nanoparticle (LNP) formulation and encapsulation services are designed to support a wide range of payloads, offering precision, reproducibility, and performance, without requiring in-house formulation expertise.

LNP Encapsulation for Diverse Payloads

We specialise in encapsulating the following types of payloads using lipid nanoparticles, a proven and scalable delivery system for nucleic acid-based therapeutics and small molecules:

• mRNA – for vaccines, gene editing, and protein replacement therapies
• siRNA / RNAi – for gene silencing and functional genomics
• Oligonucleotides – including antisense and aptamers
• Small Molecules – for targeted delivery and improved bioavailability
• Other Payloads – available on request

Whether you’re in early-stage discovery or preclinical development, we adapt our approach to your specific needs.

Figure 1: Transfection of encapsulated eGFP mRNA in the 3D model​

mRNA expression (eGFP) and LNPs fate (Cy3) after 48h – F4​

1. Consultation – Understanding Your Payloads & Objectives

We begin with a collaborative discussion to understand your project goals, payload type, and delivery requirements.
Together, we define the optimal formulation strategy based on your intended application, timeline, and regulatory context.

You share your vision, and we translate it into a technical roadmap.

2. Formulation Design – Custom LNP Strategy Development

Our experts design a bespoke LNP formulation, carefully selecting lipid components, ratios, and encapsulation techniques to achieve the highest efficiency, stability, and biological performance.

You benefit from advanced formulation know-how, no need for internal development capacity.

3. Encapsulation & Quality Control – Precision & Reliability

Encapsulation is performed using state-of-the-art technologies, followed by stringent quality control. Each batch is tested for particle size, encapsulation efficiency, polydispersity, and payload integrity.

You receive validated, reproducible results, without managing the technical complexity.

4. Delivery – Ready-to-Use LNPs, Shipped to You

Once validated, your encapsulated payloads are shipped directly to your lab — ready for immediate use in in vitro assays, animal studies, or further development.

You get a turnkey solution, no formulation, no troubleshooting, just results.