The Blood-Brain Barrier (BBB) affects the development of drugs for all pathologies (brain exposure to drugs, side effects...). In the early phases of drug development, there is a strong need for stable

The unprecedented increase in antibiotic-resistant pathogens

Protein Gene Product 9.5 (PGP 9.5) is an abundant cytoplasmic neuron and neuroendocrine-cell specific protein. Over the years, this deubiquitinating enzyme (a.k.a. Ubiquitin Carboxy-terminal Hydrolase

Focus Biomolecules produces a broad range of bioactive lipid mediators as well as many small molecule inhibitors of numerous lipid metabolic pathways for use as cellular

Cell-Based ELISA tests now enable precise measurement of the phosphorylation status or expression profiles of target proteins (biomarkers) in whole cells. In this post, a review of high performing cell-based assays is made.

Interestingly, the experimental design is simple and is based on 3 steps:

1. Plate
2. Treat and fix your cells of interest (adherent or in suspension)
3. Detect the target proteins with the optimized reagents provided in the kit (450 nm colorimetric detection)

These Colorimetric Cell-Based ELISA Kits enable the detection of various target proteins (biomarkers). Some references also enable the precise measurement of the phosphorylation status of proteins of interest. They can easily

In the field of neurosciences, increasing research is being undertaken on neurodegenerative disorders like Parkinson’s and Alzheimer’s diseases, as well as on nerve injury and regeneration. One of the

Plasmid preps are to science what salt is to cooking. They're so common that nobody notices, but nothing can be done without them. There is no mention of this step in any published paper, nobody mentions

As detailed in a separate post, bit.bio have developed a novel cellular reprogramming technology, opti-ox™

More than two years ago, the whole planet got impacted by COVID-19. Over time, and with the help of our dedicated worldwide scientific research community, we have learnt how to prevent its spread and to

mRNA is a ribonucleic acid used by cells as an intermediate carrier of the genetic information contained in the DNA to synthesize proteins, and corresponds to the copy of one of the two strands of DNA.

Mitochondrial Dynamics and Mitochondria-Lysosome Contacts in Neurogenetic Diseases

In an article published in frontiers in Neuroscience, with the aim to study cellular phenotypes