CHO-K1/DP1/Gα15 Stable Cell Line - 2vials
DP1 is a Gs-coupled GPCR expressed in the colon, eye, platelets, eosinophils, that bind to PGD2 and PGE2. DP1 can inhibit platelet aggregation, and also inhibit leukotriene B4 and superoxide anion (O2-) release from human neutrophils. It can relax smooth muscle and regulate eosinophil apoptosis. DP receptor knockout OVA-challenged mice exhibit reduced Th2 cytokine levels and lymphocyte accumulation in the lung. In addition, they failed to produce asthmatic responses.
Supplier Catalog Number |
M00453 |
---|---|
Shipping conditions |
Dry ice |
Storage Temperature |
-180°C |
Supplier name |
Genscript Biotech B.V. |
From
€10,200.00
Total
€10,200.00
In stock
- SKU
- P00780862::2vials
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