Results for Chemicals ( 21800 )
SH2-Domain containing inositol 5-phosphatases (SHIP1 & SHIP2) dephosphorylate the 5-position of PI(3 4 5)P3 generating PI(3 4)P2. SHIP2 is ubiquitously expressed while SHIP1 is found in hematolymphoid cells and mesancymal stem cells. K118 is a water soluble SHIP1 inhibitor which does not inhibit SHIP2. Treatment with K118 (10 mg/kg) on obese mice on a high fat diet resulted in reduced body mass and lowered fat content when compared to pre-treatment and non-treated control animals. The treated mice had reduced blood glucose and insulin levels in addition to improved glucose tolerance. K118 treatment also reduced the amount of age-related fat accumulation in mice.
Farnesoic acid ((2E 6E)-3 7 11-trimethyldodeca-2 6 10-trienoic acid) is the substrate of farnesoic acid O-methyltransferase which produces the crustacean reproductive hormone methyl farnesoate (MF). MF is responsible for enhancing reproductive maturation maintaining juvenile morphology and influencing male sex determination. Farnesoic acid also inhibits filiment formation in C. albicans. Powered by Bioz See more details on Bioz
Methyl farnesoate (MF) is a crustacean reproductive hormone that is structurally similar to insect juvenile hormone. It is responsible for enhancing reproductive maturation maintaining juvenile morphology and influencing male sex determination. Exposure of female Daphnids to increasing levels of MF increases the percentage of males in a brood in a dose-dependant manner. MF is endogenously produced in the mandibular organ and environmental factors such as salinity and temperature can influence hemolyph levels. Powered by Bioz See more details on Bioz
Sodium Hyaluronate is the sodium salt of hyaluronic acid (HA) also known as hyaluronan a glycosaminoglycan consisting of D-glucuronic acid and N-acetyl-D-glucosamine disaccharide units. HA is one of several glycosaminoglycan components of the extracellular matrix of connective tissue. HA is a naturally occurring biopolymer involved in numerous biological processes including tissue hydration and structural scaffolding. HA is increasingly used as a reagent and investigated in medical pharmaceutical and bioengineering applications. Its use as a reagent includes hydrogels for use in aesthetics ophthalmology rheumatology urology wound healing and 3D bioprinting.Our medical grade Sodium Hyaluronate is produced by HTL by fermentation of a Streptococcus equi strain (Group C of the Lancefield Classification / Non GMO / Without any material from animal origin). HTL’s proprietary process allows the production of Sodium Hyaluronate fiber with an exceptionally low level of impurities. HTL