Peptides & Amino Acids

gp100 (280-288) A288V HLA-A*0201 antigen peptide – YLEPGPVTV SB-PEPTIDE offers gp100 (280-288) A288V variant peptide – YLEPGPVTV for its promising use in immunotherapy. gp100 protein: potent melanoma-specific antigen gp100 (Uniprot: P40967) 661 amino acids long type I transmembrane glycoprotein, also known as premelanosome protein (PMEL) for the gene encoding it, is primarily known for its crucial role in melanosome morphogenesis and pigmentation. Indeed, it orchestrates the maturation of these organelles, that are responsible for melanin synthesis, storage, and transport. More than its implication in melanosome maturation, melanogenesis, biogenesis, and melanin polymerization, gp100 has gained significant attention and recognition as tumor-associated antigen (TAA). Hance, its dynamic and multifaceted nature piqued the interest of researchers and immunobiologists to explore PMEL’s potential in shaping the future of cancer treatment. gp100 280-288 immunogenic epitope – YL

Biotin-PEG-Thiol (MW 2000) is an active, pegylated compound that binds to streptavidin or antibiotin with high affinity and specificity. It is capable of modifying biomolecules, proteins, peptides, and other small molecular materials. This compound is commonly utilized in agent release research and the development of novel nanomaterials [1].