Nucleotides

The 2'-O-MOE-5MeU-3'-phosphoramidite, a monomer with 2'-O-MOE, builds antisense RNA via oligonucleotide phosphoramidites. Its 2'-MOE backbone strengthens duplexes, resists nuclease, and has minimal toxicity.

1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phos-phino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-ß-D-ribo-hex-5-enofuranosyl]uracil is a modified nucleotide with a phosphate at the 5' position and an acetyl group in place of the hydroxyl group at the 2' position. Reagent grade, for research purpose.

5'-O-DMTr-2'-O-TBDMS-5-methoxyuridine-3'-(cyanoethyl-N,N-diisopropyl)phosphoramidite is a TBDMS-protected phosphoramidite monomer suitable for building oligoribonucleotides.

2'-O-MOE-A(Bz)-3'-phosphoramidite inserts 2'-O-methoxyethyl-modified adenosine into oligonucleotide phosphoramidites for antisense RNA. Its 2'-MOE backbone bolsters duplex stability, nuclease resistance, and has low toxicity, contributing to effective, safe genetic manipulation.

3-Cyanovinylcarbazole Phosphoramidite can be used to form DNA strands incorporating cyanovinylcarbazole components.

2'-Fluoro-5MeC (Bz)-3'-phosphoramidite is a purine nucleoside amidite analog that can be used to produce oligonucleotides.

2'-OMe-G(iBu)-3'-phosphoramidite is a chemically unstable and heat-sensitive nucleoside phosphoramidite that serves as a foundational element in oligonucleotide synthesis.

2'-O-Propargyl G(iBu)-3'-phosphoramidite, containing propargyl and benzoyl groups, readily attaches to diverse biomolecules. Through click chemistry, its reactive propargyl unit conjugates with azide-linked compounds, enabling versatile molecular binding for conjugation.

2'-O-Propargyl A(Bz)-3'-phosphoramidite includes exceptional propargyl and benzoyl functionalities that allow it to easily bind to a wide range of biomolecules. The propargyl unit, utilizing click chemistry, reacts with azide molecules for conjugation purposes.